ABSTRACT
Objective. The SARS-CoV-2 pandemic has changed the therapeutic relationship between women and midwives and these changes have been perceived as stressors. The aim of this work is to investigate the effect of these stressors on midwives through an online questionnaire. Materials and Methods. The VRS tool was used, and statistical analysis was performed using Stata. Results. Significant differences were found in the somatization cluster and in subjective stress cluster. Conclusions. The analysis shows that there is a need to implement resilience-enhancing factors such as communication, sharing of distress and the presence of support. Copyright © 2022, EDRA S.p.A. All rights reserved.
ABSTRACT
Background In 2020, the total deaths from all causes were the highest ever recorded in Italy since World War II (15.6% excess), with peaks during Sars-Cov2 waves and reductions in periods of national lockdown. On the contrary, in 2021, the total number of deaths from all causes reduced compared to the previous year. Analysing local mortality data, our study aims to assess whether, in the Casentino Valley (Arezzo, Tuscany), an excess of deaths from all causes occurred between January 2020 and December 2021 compared to the five years 2015-2019. Methods We used the official mortality data from the Italian Institute of Statistics (ISTAT), and that are published in the Table of deaths by the municipality on March 2, 2022. From this database, we extrapolated all deaths from all causes between January 1, 2020, and December 31, 2021, in the 10 municipalities of Casentino. The data collected were processed using Microsoft Excel 2016 software. We then distinguished by total per month, gender, and age group and then compared these data with the previous five years’ average by calculating the percentage change. Results Overall, both the years 2020 and 2021, it is shown an increase in the deaths percentages compared to the previous five-year period, respectively 5.66% and 8.07%. In particular, there is an excess of mortality in November and December 2020. The increase in mortality is more remarkable for males (13% in 2020 and 20% in 2021). The highest percentage increase was recorded in 2021 for the 75-84 age group (+15%) and in 2020 for males over 85 (+29%). Conclusions The data analysed confirms the excess mortality in 2020-2021 compared to the average of the previous 5 years in Casentino. There are peaks in November and December 2020, corresponding with the second wave of Sars Cov2 infection. The results obtained establish the basis for subsequent analyses that will verify the correlation of mortality peaks with the incidence of Sars-Cov2 cases in the territory studied. Key messages • Between January 1, 2020, and December 31, 2021 there was an excess of all-cause mortality in our area. • This excess mortality appears to be related to peaks in Sars-Cov2 infection.
ABSTRACT
Background In the area of the Local Health Authority Toscana Sud-Est (LHA) 13,5% of residents are foreigners. We aim to assess the impact of our intervention to COVID-19 vaccination coverage. Methods Since summer 2021, LHA has promoted vaccination sessions dedicated to foreign residents with free walk-in access, multilingual forms, flyers and TV interventions, cultural mediators and trained healthcare workers. We collected data about vaccination status of residents (28 December 2020-31 January 2022) and we analysed them using the software STATA to assess vaccine coverage by nationality and the effectiveness of our intervention. The results were adjusted for age and sex. We set significance level at p < 0.05. Results On 31 July 2021, 78% of Italian residents (N = 685289) had received the first dose of vaccine, compared to only 43% of foreign residents (N = 106370). There was a 35% gap. On 31 January 2022, after our intervention, 89% of Italian residents and 71% of foreign residents had received the first dose of the vaccine. The gap was 18%. On 31 January 2022, 50% of residents of all nationalities had received two doses of the vaccine. A significant difference between Italian and foreign residents is still observed after adjustment for age and sex (OR 0.41 95% IC 0.40-0.41). Vaccination adherence is lower in females than males, for both Italian (OR 0.90 0.89-0.91) and foreign residents (OR 0.82 0.79-0.84). This is accentuated within some ethnic groups: Macedonians, Kosovars, Pakistanis. Conclusions The creation of dedicated service guaranteed to reach a high vaccination coverage in all the nationalities and to reduce the gap between host and foreign residents. In foreigners it is lower than in the hosts, so it is necessary to investigate possible cultural factors that may influence hesitancy. A lower vaccination coverage in females, especially in foreigners, may be due to an inferior participation in social and working life as a consequence of the gender gap. Key messages • The creation of dedicated interventions guaranteed to achieve high vaccination coverage in all nationalities. • A lower vaccination adherence in females than males, especially in foreigners, may be due to an inferior participation in social and working life as a consequence of the gender gap.
ABSTRACT
Background In Italy, the flu vaccine is recommended and free for target groups (adults≥60 years old, fragile people, healthcare workers, pregnant women). During the 2020/2021 flu season, an increased vaccination coverage (+6,9%) was observed compared to the previous season, also due to the Covid-19 pandemic. We aimed to investigate how strong the adherence to the flu vaccine was by the vulnerable groups and assess if the Covid-19 vaccination campaign may have influenced the rate of flu vaccines. Methods At the beginning of autumn 2021 we conducted an online survey among the population of Tuscany. We collected data on demographics, health status (pregnancy, vulnerable), flu and COVID-19 vaccinations coverage and health information sources. In addition, we performed a descriptive and a risk factors analysis to assess correlation between our variables with R v 4.0.0. Significance level was set at p < 0.05. Results Among 408 participants, 248 (61%) belong to a vulnerable group and are recommended to receive the flu vaccine, 229 (56%) usually get the flu vaccine, 386 (95%) got the Covid-19 vaccine, 267 (65%) choose and trust the general practitioner (GP) as their health information source. There is a statistically significant association between being part of a vulnerable group and getting the seasonal flu vaccine (OR 6.63 95% CI 4.26-10.3 p < 0.001). In addition, getting the Covid-19 vaccine increases the likelihood of receiving the flu vaccine (2.90 95% CI 1.16-7.28 p = 0.018). Moreover, participants who trust their GP as their health information source (OR 1.63 CI 1.08-2.46 p = 0.019) are more likely to receive the flu vaccine;other information sources (TV, newspaper, social media) are not associated with the flu vaccine. Conclusions Our research shows that vulnerable groups get vaccinated against the flu. The increase in flu vaccine coverage may be due to the COVID-19 vaccines campaign. GPs play a crucial role in the health promotion, prevention and health literacy of patients. Key messages GP plays a crucial role in the prevention and health literacy of patients. COVID-19 vaccines campaign may have positively influenced the flu vaccination campaign. However, we must continue to maintain the coverage we have managed to achieve in the future.
ABSTRACT
Introduction CoViD19 pandemic highlighted the importance of air purifiers and, in commercialization, their performance and price influence the choice. Since primary focus concerns only performance in terms of CADR (Clean Air Delivery Rate), this study aims to compare: I) levels of declared air purifications according to different types of air purification technologies;II) price of them to evaluate if, with similar group-mean CADR (within +/- 1 SD), there are significant differences in selling prices. Methods A review of several devices was carried out, collecting data in January-April 2022. Four different types of air purifiers were considered, divided into as many groups: those equipped with HEPA filters + UV lamps, only with HEPA filters, only with UV lamps and those using other technologies. We applied Kruskal-Wallis test to evaluate statistical differences among prices normalized by CADR, at significant level of 0.05. Results Analysis was carried out on 186 devices: I) 37 had HEPA filters + UV lamps, II) 117 only HEPA filters, III) 11 only UV lamps and IV) 21 other technologies. Eight system had HEPA H11 (95% reduction of particle matter 0.5 μm), 8 had HEPA H12 (99.5%), 70 had HEPA H13 (99.95%), 11 had HEPA H14 (99.995%). The mean normalized costs of each group devices, in Euros/CADR were I) 1.22 (SD 2), II) 1.49 (SD 1.4), III) 7.63 (SD 7.38), IV) 1.22 (SD 0.99), respectively. Statistical comparison of four-group selling prices show significant differences (p < 0.05) due to the devices equipped with only UV lamps. Conclusions Comparison between technologies analyzed by mean price normalized to CADR showed significant differences between those that used only UV lamps compared to all the others. This is reasonably due to the fact that the use of only UV lamps requires radiant powers considerably greater than all the others, therefore also higher costs (about 5-6 times). In all cases, the level of disinfection reached, as declared, was always > 95%. Key messages • With the same mean price normalized to CADR, the selling price is significanly different only for devices equipped with UV lamps compared to all the others. • Choice of devices with a certain level of declared air purifications can be directed towards those with HEPA+UV/HEPA/other without the mean price normalized to CADR undergoing significant differences.
ABSTRACT
Background The global outbreak of COVID-19 has resulted in the closure of stadiums and the interruption of Serie A for three months. Many studies have evaluated the effects of COVID on population health, but few have evaluated the effects of containment measures on the health of football players. With this study, we evaluated the impact of this break on Serie A football players. Methods This cross-sectional study was conducted considering a timespan of three Serie A seasons (2018-19;2019-20;2020-21). The information was obtained from the German website Transfermarkt. All the players who had played at least one match during each of the Serie A season were identified. For each of the players, data concerning the number of days lost due to injury, both before and after the stop in the championship due to Covid, were collected. Statistical analysis was performed using Stata 17 Software. Results According to the selection criteria, 264 players were selected. This group was subsequently skimmed to 256 players after eliminating all players who did not suffer physical injuries over the timespan considered (non-purely orthopedic surgery;COVID;Intestinal problems;Infections). 256 players were analysed, 228 had skipped at least one day for pre-lockdown due to physical injury (median=37,5), while 227 missed a day for post-lockdown (median=27). Wilcoxon signed-rank test between days lost due to injuries before and after lockdown highlighted significant differences (p < 0.05). Conclusions Comparing pre-lockdown and post-lockdown periods, we noticed that there were fewer days skipped due to physical injury post lockdown. Statistical evidence suggests that the same players were more susceptible to suffer physical injuries in the pre-lockdown period. This is probably because some players have worked with home coaching by spending more time in the gym and less time on the field. Also tapis roulant and cyclettes were often delivered to football players’ homes. Key messages In this phase of coexistence with COVID-19 it is of fundamental importance to understand the impact that public health measures have on the population. Although, with vaccination, there has been a reduction in the number of cases, it is critical to strengthen preparedness against all possible epidemic scenarios.
ABSTRACT
Introduction The COVID-19 pandemic has demonstrated how the optimal allocation of the limited doses of vaccine available represents one of the main useful measures to mitigate the transmission of the infection and reduce the mortality associated with it, especially at an early stage of the pandemic. The use of a compartmental model allows us to understand which population groups to vaccinate and to what extent to act depending on the type of health or social objective to be achieved. Methods A time-varying susceptible-infected-recovered-deceased (SIRD) compartmental model, stratified into ten age groups, was developed on Italian data. Simulations were performed every 15 days from December 2020 to April 2021. An optimal vaccination strategy was achieved by minimizing deaths or infected, considering the total vaccine doses available. Results We showed how the effects of a vaccination campaign can be planned in a way that maximizes lives saved and/or minimizes infections. Regarding the minimization of deaths, the model prioritizes the elderly (>80 years) and then those between 60 and 80 years, in all simulations. Regarding the cost function of new infections, the first simulation assigns all available doses to those over 90 years of age. In the later simulations, the doses are assigned mainly to the 20-29-year-old and the 89+ year old. Conclusions Optimal allocation of available vaccine doses is useful in mitigating transmission of infection and reducing mortality. Application of the mathematical model can be useful at the beginning of an epidemic caused by a new pathogen, when data are scarce, and it is therefore necessary to introduce a standardized approach. This kind of simulation is useful to understand whether the implemented vaccination strategy needs to be recalibrated, too. Key messages • Time-varying compartmentalised models can be used both to continuously inform decision-makers about changes in epidemic traits and to simulate the effects of targeted pandemic containment strategies. • The application of compartmental models can be very useful at the onset of an epidemic to more successfully contain it and structure the health, political, and economic plan.
ABSTRACT
Background In this historical period, it has become very important to live in healthy environments. By using everyday objects, cross-contamination is possible because of prolonged microbial persistence on surfaces. UV-C irradiation is an environmentally friendly method to disinfect objects as no harmful chemicals or heat are involved. This study aims to determine the virucidal activity, against SARS-CoV-2, of UV-C irradiation occurring in a designed UV device, ‘Purity Capsule'. Methods An experimental study was performed in September 2020. The ‘Purity capsule’ has an 11 W lamp (3.5W UV-C) positioned in the centre of the device. The lamp has a dome covered with a reflective, protective coating. Three metal carriers were placed at the maximum distance from the UV-C lamp in three different positions and tested at 30 and 60 seconds 3 times. The carriers were inoculated with 100 µL of SARS-CoV-2 viral suspension with a concentration of 106.5 TCID50 /mL. After treatment, laboratory procedures were used to transfer the treated virus from carriers to multiwell plates. The samples were compared with positive controls (not exposed to UV-C light) after incubation, at 37 °C in 5% COÕ · in a humidified atmosphere, for 3 days. The residual viral activity was tested by assessing the 50% infectious dose per tissue culture (TCID50%). Results Tests performed at 30 seconds of UV-C irradiation show an average viral reduction of 4.0 Log10 (99.99%). All three tests performed at 60 seconds reached the maximum measurable log10 viral reduction: 5.0 Log10 (99.999%). Conclusions The study assessed the effectiveness of the device in significantly reducing the viral load on all carriers regardless exposure time and distance from the UV-C light source, with no impact on the level of environmental pollution. Key messages • UV-C light has the property of inactivating viral growth;its physical approach is considered a good compromise between cost and effectiveness. • The device was effective in disinfecting all small everyday objects tested.
ABSTRACT
Background Surface sanitation is one of the key points to reduce the risk of transmission both in healthcare and other public spaces. UV-C is already used in hospital and laboratory's disinfection procedure furthermore some recent studies show effectiveness on SARS-CoV-2. UV-C may be generated by Lamps and Light Emitting Diode, but novel sources are emerging. The aim of the study was to test a device having UV chips for inactivating SARS-CoV2. Methods The descriptive study was conducted in the period between June and July 2019, in laboratories of the University of Siena and of the scientific park of Toscana life sciences. The device, shaped in a rectangular box, contained six UV chips (10 mW each, with a peak at 264nm nm ranging from 260 to 350 nm) placed in the bottom. Central and short side long positions were tested expecting different dose levels. Each experiment was conducted in triplicate, with and without the device lid, at 3, 6 and 10 minutes. All repetitions were tested for SARS-CoV-2 having a virus suspension of 10
ABSTRACT
Introduction Avoidable Mortality is an indicator of the effectiveness of Health Services. We know that Gross Domestic Product (GDP) and other macroeconomic indicators are related to health indicators. The aim was to study the impact of economic indicators on Avoidable Mortality, in Italy, with attention to the periods following the economic crisis and COVID-19 epidemic. Methods GDP, Gini Coefficient (GC) and other economic and epidemiologic data were collected from the beginning of the Century up to the present from the Italian National Institute of Statistics database (ISTAT) and the Italian National Institute of Health (ISS). Mortality data (597 causes coded by ICD-9) was divided in Preventable, Amenable and Avoidable categories. Spearman's rank Correlation Coefficient was carried out with STATA software. The analysis was performed, also using JOINPOINT software, on the entire Italian territory and then specifically on the 20 Regions. Results GDP trend showed two decreasing phases occurred between 2008-2009 and 2012-2013. A negative correlation (p.<0.05) has been demonstrated in 7 Regions between GDP values and Avoidable Mortality, 5 Regions for Preventable and Amenable Mortality. GC showed a fluctuating but growing trend without any correlation with all categories of Avoidable Mortality. In 2020, after the start of the COVID-19 pandemic (in February 2020 in Italy), GDP and Employment Rate (ER) declined rapidly, but not always homogeneously. Conclusions The upward trend of the GC reflects an increase in inequality in the period following the economic crisis. GDP trend reflects the phases of the economic crisis impacting on epidemiological indicators with a latency of about 4 years. The negative correlation between GDP and Avoidable Mortality can not be observed in all Regions. This may be explained by heterogeneous administrative policies and different levels of resilience among Regions: another description of the “european microcosm” represented by Italy. Key messages The impact of the economic crisis on Avoidable Mortality has about 4 years of latency. COVID-19 pandemic has a faster impact on GDP and ER. Italian Regions show different levels of resilience.
ABSTRACT
The coronavirus SARS-CoV-2 pandemic has become a global health burden. Surface sanitation is one of the key points to reduce the risk of transmission both in healthcare and other public spaces. UVC light is already used in hospital and laboratory infection control, and some recent studies have shown its effectiveness on SARS-CoV-2. An innovative UV chip technology, described in Part I of this study, has recently appeared able to overcome the limits of old lamps and is proposed as a valid alternative to LEDs. This study was designed to test the virucidal activity on SARS-CoV-2 of a device based on the new UV chip technology. Via an initial concentration of virus suspension of 10<sup>7.2</sup> TCID<sub>50</sub>/mL, the tests revealed a viral charge reduction of more than 99.9% after 3 min;the maximum detectable attenuation value of Log<sub>10</sub> = 5.7 was measured at 10 min of UV exposure.